MDMA analogues

MDMA is a semi-synthetic drug belonging to the group of phenylethylamines. The chemical structure of the substance allows it to be classified as an amphetamine stimulant, although it is more correct to consider it an empathogen. To date, there are a large number of different products that are sold under the name “ecstasy”, not toRead More

Synthetic Cathinones

Structurally, synthetic cathinones are beta-ketophenitylamines similar to amphetamines/catecholamines, with minor structural changes that alter chemical properties, effects, pharmacokinetics, and pharmacodynamics. The popularity of synthetic cathinones among consumers is due to the small amount of “pure cocaine” on the shadow market, its cost, as well as legal problems associated with the use and purchase of cocaine.Read More

Amphetamines

Amphetamines are a class of compounds that includes amphetamine itself and its derivatives. Many amphetamines have notable psychoactive properties and are common drugs. Some of them are also of limited use in medicine in the treatment of ADHD and narcolepsy. Examples of amphetamine derivatives are methamphetamine, ephedrine, cathinone, methcathinone, 3,4-methylenedioxyamphetamine (MDA), 3,4-methylenedioxymethamphetamine (MDMA, “Ecstasy”), 2,5-dimethoxy-4-bromoamphetamineRead More

Pentazocine

Pentazocine (Talvin): Other names: talvin, fortral, lexir. An attempt to find an effective painkiller that does not cause addiction led to the creation of Pentazocine (talvin). Introduced in 1967 as an analgesic, it quickly appeared on the illegal market, usually in combination with tripennamine. The list of narcotic drugs subject to control in the RussianRead More

Tranquilizers

It is necessary to understand that these drugs were created as “disposable” medicines. Initially, they were conceived as symptomatic remedies for the treatment of anxiety. The authors of the historically first of them – diazepam (aka valium, seduxen, relanium, sibazone, etc.) assumed that a person who suffers from excessive anxiety can take diazepam from timeRead More

Tranquilizers. Pharmacological properties, areas of improvement, Problems of safety of use

Tranquilizers (from Lat. tranquillium — “tranquility”) represent one of the most important groups of psychotropic drugs. Recently, they are increasingly called anxiolytics (from the Latin. anxius — “anxious” and Greek. lysis — “dissolution”). There are other, less common names — ataractics (from the Greek ataraxia — “equanimity”), psychosedative, anti-neurotic drugs. In the general classification ofRead More

4-Methylaminorex

4-methylaminorex is a chemical compound derived from aminorex. It has a structural similarity with amphetamines. It produces a psychostimulating effect and is used as a drug. It can cause a dangerous irreversible complication — pulmonary hypertension. Isomers 4-methylaminorex can exist in the form of four isomers: cis-4R,5S, cis-4S,5R, trans-4S,5S, trans-4R,5R. Mechanism of action 4-methylaminorex increasesRead More

Dissociatives

Dissociative drugs belong to the class of anesthetics, which are also called “dissociative anesthetics”, since initially the purpose of their elimination was exclusively medical. The meaning of the name of drugs “dissociatives” is that these drugs disrupt and unbalance the elements of the mind, break the connections between neuroreceptors. Memory, perception, consciousness and motor activityRead More

Diazepam

Description of the active substance Diazepam. Formula: C16H13ClN2O, chemical name: 7-Chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepine-2-one. Pharmacological group: neurotropic agents, antiepileptic agents; agents affecting neuromuscular transmission; anxiolytics, benzodiazepine derivative. Pharmacological action: anticonvulsant, anxiolytic, central muscle relaxant, sedative, hypnotic. Pharmacological properties Diazepam acts on specific benzodiazepine receptors, which are located in postsynaptic GABA-receptor complexes in the thalamus, limbic system, hypothalamus, insertionRead More

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